Receptor pharmacology
Published pharmacology characterizes tesamorelin as a GHRH analogue with receptor-binding properties comparable to native human GRF. Experimental measurements relate to receptor interaction and downstream GHRH-axis signaling.
For laboratory research use only. Not for human consumption.
Free U.S. shipping on $200+GLPZone / The research collection

Nordicstar Analytical Sciences
Tesamorelin 10 MG
Nordicstar Analytical Sciences
Tesamorelin 20 MG
Repair & Recovery
GHRH receptor pharmacology & peptide stability
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For laboratory research use only.
Not for human consumption or clinical use.
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
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Shipping information01 / The compound
GHRH receptor pharmacology & peptide stability
Tesamorelin, also known by the development code TH9507, is a 44-amino-acid synthetic analogue of growth hormone-releasing hormone (GHRH/GRF). Its peptide sequence corresponds closely to human GRF(1-44), with a trans-3-hexenoyl modification at the N-terminal Tyr1 residue.
Laboratory research has examined Tesamorelin in relation to GHRH-receptor pharmacology, peptide stability, enzymatic resistance and signaling within the GH/IGF-1 axis. The N-terminal modification is an important structural feature because it was developed to alter stability relative to native GHRH.
02 / Research profile
Published pharmacology has characterized Tesamorelin as a GHRH analogue with receptor-binding properties comparable to native human GRF. Research has examined the compound within the GHRH signaling pathway and downstream GH/IGF-1 biology.
GHRH / GRF receptor
Human GRF(1-44) sequence
Trans-3-hexenoyl group at Tyr1
GHRH receptor signaling → GH-axis activity → downstream IGF-1 measurements
This pathway summarizes areas evaluated in published research and is not a human-use protocol or therapeutic recommendation.
Research measurements follow different stages of the pathway, from GHRH-receptor interaction to downstream GH-axis activity and IGF-1 measurements. These endpoints describe experimental pharmacology and do not establish equivalence between different tesamorelin formulations.
Published pharmacology characterizes tesamorelin as a GHRH analogue with receptor-binding properties comparable to native human GRF. Experimental measurements relate to receptor interaction and downstream GHRH-axis signaling.
The trans-3-hexenoyl group at the N-terminal Tyr1 residue is a defining modification studied in relation to peptide stability and resistance to enzymatic degradation.
Reading the evidence
The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.
03 / Reference data
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | Tesamorelin |
|---|---|
| Research area | Repair & Recovery |
| CAS number | 218949-48-5 |
| Molecular formula | C223H352N44O50S |
| Molecular weight | 5135.85 g/mol |
| Physical form | Lyophilized |
| Vial options | 10 MG · 20 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Every Tesamorelin lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 10 MG Current lot | GLZ-26-TESA-1046 | 99.696% | 23 Sep 2026 | NS-2026-06047 |
| 20 MG Current lot | GLZ-26-TESA-1047 | 99.603% | 14 Sep 2026 | NS-2026-06048 |
| 20 MG | GLZ-26-TESA-753 | 99.647% | 18 Aug 2026 | NS-2026-06167 |
| 10 MG | GLZ-26-TESA-754 | 99.571% | 16 Aug 2026 | NS-2026-06165 |
| 10 MG | GLZ-26-TESA-654 | 99.609% | 13 Jul 2026 | NS-2026-06166 |
| 20 MG | GLZ-26-TESA-653 | 99.768% | 11 Jul 2026 | NS-2026-06168 |
05 / Storage & handling
Tesamorelin is supplied as lyophilized research material. Storage and stability requirements can depend on the specific formulation, packaging and manufacturer-supported stability data.
Product-specific documentation is required to establish a storage temperature, preparation method or solution stability period.
Explore the handling guide06 / Common questions
Tesamorelin, also known as TH9507 or TH-9507, is a 44-amino-acid synthetic analogue of human GHRH/GRF. It contains a trans-3-hexenoyl modification at the N-terminal Tyr1 residue.
Tesamorelin closely follows the human GRF(1–44) peptide sequence and contains an N-terminal trans-3-hexenoyl modification. This distinguishes its molecular design from native GHRH and from the shorter GHRH(1–29) analogues.
07 / Further reading
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
Curated pairings