For laboratory research use only. Not for human consumption.
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Illustrative certificateNS-2026-06062Nordicstar Analytical Sciences
KPV 10 MG
Immunology
α-MSH fragment & epithelial signaling research
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For laboratory research use only.
Not for human consumption or clinical use.
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.
Shipping information01 / The compound
α-MSH fragment & epithelial signaling research
KPV is the tripeptide Lys-Pro-Val, a three-amino-acid sequence corresponding to residues 11–13 at the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH).
Published research has examined KPV in cellular and animal models involving inflammatory signaling, intestinal epithelial transport, mucosal responses, keratinocyte signaling and antimicrobial activity. KPV represents the C-terminal tripeptide sequence of α-MSH and has been investigated separately from the complete parent peptide.
Research into KPV’s signaling mechanisms remains ongoing. Experimental studies have examined pathways involving PepT1 transport, NF-κB, MAPK, cytokine signaling and melanocortin-related mechanisms. Findings should be interpreted within the individual cell, animal or laboratory systems used in each study.
02 / Research profile
Published KPV research spans several experimental areas, with the strongest body of direct evidence involving inflammatory signaling and intestinal models. Most published KPV evidence remains preclinical.
KPV has been investigated in intestinal epithelial cells, immune-cell systems and experimental models of intestinal inflammation. Published work has examined PepT1-mediated cellular uptake and signaling involving NF-κB, MAPK and pro-inflammatory cytokine expression. Separate animal studies have examined KPV in experimentally induced intestinal inflammation, including models involving nonfunctional MC1R signaling.
Experimental studies have compared the C-terminal KPV sequence with full α-MSH and other melanocortin-related peptides. Cell and animal studies indicate that KPV signaling does not simply reproduce the classical cAMP response associated with the complete α-MSH peptide. The mechanisms responsible for the experimental effects observed with KPV remain an active area of research.
KPV has also been examined in cultured human keratinocyte models and other epithelial research systems. Separate in-vitro studies have investigated α-MSH-derived peptides, including KPV, against organisms such as Staphylococcus aureus and Candida albicans.
Reading the evidence
Evidence context: Published KPV research is predominantly preclinical, including cell-based, in-vitro and animal studies. Findings should be interpreted within the experimental models and conditions used in each publication.
03 / Reference data
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | KPV |
|---|---|
| Research area | Immunology |
| CAS number | 67727-97-3 |
| Molecular formula | C21H30N6O4 |
| Molecular weight | 430.51 g/mol |
| Physical form | Lyophilized |
| Vial options | 10 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Every KPV lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 10 MG Current lot | GLZ-26-KPV-1061 | 99.621% | 18 Sep 2026 | NS-2026-06062 |
| 10 MG | GLZ-26-KPV-739 | 99.568% | 11 Aug 2026 | NS-2026-06195 |
| 10 MG | GLZ-26-KPV-639 | 99.682% | 10 Jul 2026 | NS-2026-06196 |
05 / Storage & handling
Keep unopened lyophilized KPV protected from heat, moisture, light, and repeated temperature changes. Follow the storage conditions supplied with the product and applicable lot documentation.
Use validated laboratory storage procedures for the specific material.
Explore the handling guide06 / Common questions
KPV stands for Lys-Pro-Val, a three-amino-acid peptide corresponding to the C-terminal α-MSH(11–13) sequence. Published research has primarily examined KPV in cell-based, in-vitro and animal models involving inflammatory signaling, epithelial transport and barrier-tissue biology.
KPV is also described in scientific literature as Lys-Pro-Val, α-MSH(11–13) or MSH(11–13). Its amino-acid sequence is KPV.
07 / Further reading
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
Curated pairings
