For laboratory research use only. Not for human consumption.
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Illustrative certificateNS-2026-06071Nordicstar Analytical Sciences
VIP 10 MG
Other Compounds
VPAC receptors, circadian coordination & cell signaling
A pair saves 10%. A set of three saves 15%.
For laboratory research use only.
Not for human consumption or clinical use.
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.
Shipping information01 / The compound
VPAC receptors, circadian coordination & cell signaling
Vasoactive intestinal peptide, or VIP, is a 28-amino-acid neuropeptide studied across neural, gastrointestinal, circadian and immune signaling systems. VPAC1 and VPAC2 are its principal high-affinity receptor targets.
The same signaling peptide is investigated in several tissue contexts. Receptor expression, cellular environment and downstream coupling matter when interpreting a result obtained in one experimental model.
02 / Research profile
VPAC1 and VPAC2 belong to the class B1 family of G protein-coupled receptors. Structural and pharmacological studies examine peptide recognition and receptor-specific coupling rather than treating every VIP response as a single, uniform effect.
VIP is studied primarily through the VPAC1 and VPAC2 receptors, two class B1 G protein-coupled receptors. Modern structural and pharmacological research has examined how VIP engages these receptors and how receptor-specific interactions influence downstream cellular signaling.
VIP is widely studied as a signaling peptide in the nervous and gastrointestinal systems. Research has examined its involvement in intestinal secretion and motility as well as neuronal and neuroendocrine signaling. Within the suprachiasmatic nucleus, the principal mammalian circadian clock, VIP/VPAC2 signaling has been shown to contribute to cellular synchronization and coordinated circadian rhythmicity.
VIP and its receptors have also been investigated in experimental immune-cell systems. Cell-based research has examined VPAC1- and VPAC2-associated receptor coupling, second-messenger signaling, kinase activation, transcriptional responses and cytokine-related pathways. These responses vary according to receptor expression, cell type and experimental conditions and should not be interpreted as evidence of a therapeutic effect.
Reading the evidence
The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.
03 / Reference data
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | VIP |
|---|---|
| Research area | Other Compounds |
| CAS number | 40077-57-4 |
| Molecular formula | C147H237N43O43S |
| Molecular weight | 3326.80 g/mol |
| Physical form | Lyophilized |
| Vial options | 10 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Every VIP lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 10 MG Current lot | GLZ-26-VIP-1070 | 99.594% | 22 Sep 2026 | NS-2026-06071 |
| 10 MG | GLZ-26-VIP-730 | 99.763% | 12 Aug 2026 | NS-2026-06213 |
| 10 MG | GLZ-26-VIP-630 | 99.649% | 17 Jul 2026 | NS-2026-06214 |
05 / Storage & handling
Keep sealed research material protected from moisture, unnecessary light and temperature fluctuations. Use the storage conditions documented for the specific compound, formulation and lot.
Solution stability depends on solvent, concentration, container and experimental conditions. Use a validated laboratory protocol; a universal post-reconstitution shelf life is not established by the literature summaries.
Explore the handling guide06 / Common questions
VIP stands for Vasoactive Intestinal Peptide, a 28-amino-acid neuropeptide studied across receptor signaling, neural, gastrointestinal, circadian and immune research. Two of its principal high-affinity receptors are VPAC1 and VPAC2.
VIP/VPAC2 signaling has been studied in the suprachiasmatic nucleus, where it contributes to synchronization between cellular clocks and coordinated circadian rhythmicity in experimental models.
No. Receptor expression and downstream coupling differ across cell types. The cited immune-cell work examines second messengers, kinases, transcriptional responses and cytokine-related pathways under specified experimental conditions.
07 / Further reading
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
Curated pairings
