Melanocortin Receptor Signaling
PT-141 is a melanocortin receptor agonist investigated across multiple receptor subtypes. Earlier PT-141 research focused particularly on MC3R and MC4R because of their expression in the central nervous system.
GLPZone / The research collection
Illustrative certificateNS-2026-06068Nordicstar Analytical Sciences
PT-141 10 MG
99.628%HPLC purity
- Lot
- GLZ-26-PT141-1067
- Measured content
- 10.07 mg
- Mass-spec identity
- Confirmed
- Endotoxin
- <1.0 EU/mg
- Tested
- 24 Sep 2026
Other Compounds
PT-141
Bremelanotide · melanocortin receptor research
A pair saves 10%. A set of three saves 15%.
For laboratory research use only.
Not for human consumption or clinical use.
Compound details
- Compound
- PT-141
- CAS number
- 189691-06-3
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.18 g/mol
- Form
- Lyophilized
Quality & documentation
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
- Lot
- GLZ-26-PT141-1067
- HPLC purity
- 99.628%
- Measured content
- 10.07 mg
- Tested
- 24 Sep 2026
- Report
- NS-2026-06068
Shipping & handling
Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.
Shipping information01 / The compound
Understand
the starting point.
Bremelanotide · melanocortin receptor research
PT-141 is the investigational name associated with bremelanotide, a synthetic cyclic heptapeptide derived from melanocortin analogue research. Published laboratory research has examined the compound in relation to melanocortin receptor signaling and centrally mediated receptor pathways.
PT-141 should not be described as exclusively selective for MC4R. Melanocortin receptor research has examined activity across multiple receptor subtypes, including MC3R and MC4R, depending on the experimental system and assay used.
02 / Research profile
The pathways.
The possibilities.
PT-141 and bremelanotide refer to the same core peptide entity in scientific and chemical reference sources.
Reference databases distinguish bremelanotide free base from bremelanotide acetate. Product identity and analytical information should therefore be interpreted from the specific lot documentation associated with the material offered in this summary.
Preclinical Research
Preclinical melanocortin research has examined receptor activation, hypothalamic signaling and centrally mediated physiological pathways in animal and laboratory models. These studies provide mechanistic context for investigating PT-141 within the broader melanocortin receptor system.
Melanocortin Receptor Research
PT-141, also known as bremelanotide, is a cyclic melanocortin peptide structurally related to Melanotan II. Its research context is connected to the melanocortin receptor family, a group of G-protein-coupled receptors involved in multiple signaling pathways. Laboratory research on melanocortin analogues has examined receptor affinity, receptor-subtype selectivity, cyclic peptide structure and structure-activity relationships. These mechanistic areas provide the appropriate research context for PT-141 on this summary.
Reading the evidence
The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.
03 / Reference data
The details,
in plain sight.
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | PT-141 |
|---|---|
| Research area | Other Compounds |
| CAS number | 189691-06-3 |
| Molecular formula | C50H68N14O10 |
| Molecular weight | 1025.18 g/mol |
| Physical form | Lyophilized |
| Vial options | 10 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
What is in the sample?
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Is it the expected compound?
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Does the report match the vial?
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Independent analysis
Every PT-141 lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 10 MG Current lot | GLZ-26-PT141-1067 | 99.628% | 24 Sep 2026 | NS-2026-06068 |
| 10 MG | GLZ-26-PT141-733 | 99.647% | 13 Aug 2026 | NS-2026-06207 |
| 10 MG | GLZ-26-PT141-633 | 99.595% | 08 Jul 2026 | NS-2026-06208 |
05 / Storage & handling
Care for
the material.
Keep sealed research material protected from moisture, unnecessary light and temperature fluctuations. Use the storage conditions documented for the specific compound, formulation and lot.
Solution stability depends on solvent, concentration, container and experimental conditions. Use a validated laboratory protocol; a universal post-reconstitution shelf life is not established by the literature summaries.
Explore the handling guide06 / Common questions
A little more
understanding.
Is PT-141 the same as bremelanotide?
Yes. PT-141 is the investigational name commonly associated with bremelanotide in scientific and chemical reference sources. the exact tested material should be interpreted from its lot-specific analytical documentation.
Is PT-141 exclusively selective for MC4R?
No. The source research describes melanocortin receptor activity across multiple subtypes, including MC3R and MC4R. Receptor affinity and signaling depend on the assay and experimental system.
07 / Further reading
Go to
the source.
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
- 01
- 02
- 03Schiöth HB, et al. Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypes. Peptides. 1997. pubmed.ncbi.nlm.nih.gov / Published literature
- 04Compound Reference: Bremelanotide / PT-141 — PubChem CID 9941379 pubchem.ncbi.nlm.nih.gov / Published literature
Curated pairings
