For laboratory research use only. Not for human consumption.
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Illustrative certificateNS-2026-06059Nordicstar Analytical Sciences
Melanotan-2 10 MG
Healthy Aging
Cyclic melanocortin structure & receptor selectivity
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For laboratory research use only.
Not for human consumption or clinical use.
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
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Shipping information01 / The compound
Cyclic melanocortin structure & receptor selectivity
Melanotan II is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH). It emerged from structure-activity research investigating whether conformationally constrained melanocortin analogues could produce potent and prolonged activity compared with native α-MSH.
Foundational studies of cyclic α-MSH analogues reported enhanced potency and prolonged melanotropic activity in experimental bioassays.
Melanotan II is commonly abbreviated MT-II or MT2, while the spelling Melanotan 2 is also widely used.
02 / Research profile
Melanotan I and Melanotan II are related α-MSH analogues, but they are distinct compounds.
Melanotan I, also known as afamelanotide, is a longer α-MSH analogue, whereas Melanotan II is a shorter cyclic analogue developed through structure-activity research into conformationally constrained melanocortin peptides.
Their structures and receptor profiles differ, so they should not be treated as interchangeable research materials.
Melanotan II was developed through research on truncated and cyclic analogues of α-melanocyte-stimulating hormone. Early studies investigated whether structural constraint through cyclization could increase potency and prolong melanocortin activity in experimental systems.
MT-II has been evaluated across several human melanocortin receptor subtypes. Published receptor studies tested its activity at MC1R, MC3R, MC4R, and MC5R, supporting its classification as a relatively broad melanocortin receptor agonist rather than an MC1R-selective compound.
Melanotan II is a cyclic alpha-melanocyte-stimulating-hormone analogue developed through structure-activity research on melanocortin peptides. Laboratory studies have examined cyclic melanocortin analogues for receptor potency, receptor subtype selectivity and the relationship between peptide conformation and melanocortin-receptor activity. This mechanistic work provides the appropriate scientific context for Melanotan II as a research compound.
Bremelanotide, also known as PT-141, is a closely related melanocortin analogue derived from the Melanotan II scaffold. Published reviews describe PT-141 as differing from MT-II at the C-terminal group, with a carboxylic acid replacing the carboxamide found in Melanotan II.
Reading the evidence
The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.
03 / Reference data
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | Melanotan-2 |
|---|---|
| Research area | Healthy Aging |
| CAS number | 121062-08-6 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.18 g/mol |
| Physical form | Lyophilized |
| Vial options | 10 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Every Melanotan-2 lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 10 MG Current lot | GLZ-26-MT2-1058 | 99.764% | 20 Sep 2026 | NS-2026-06059 |
| 10 MG | GLZ-26-MT2-742 | 99.615% | 14 Aug 2026 | NS-2026-06189 |
| 10 MG | GLZ-26-MT2-642 | 99.758% | 12 Jul 2026 | NS-2026-06190 |
05 / Storage & handling
Keep sealed research material protected from moisture, unnecessary light and temperature fluctuations. Use the storage conditions documented for the specific compound, formulation and lot.
Solution stability depends on solvent, concentration, container and experimental conditions. Use a validated laboratory protocol; a universal post-reconstitution shelf life is not established by the literature summaries.
Explore the handling guide06 / Common questions
Melanotan II is commonly written as Melanotan 2 and is frequently abbreviated MT-II or MT2.
The cited receptor studies examine MT-II at MC1R, MC3R, MC4R and MC5R. Its research profile is relatively broad within the melanocortin family rather than exclusively selective for MC1R.
07 / Further reading
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
Curated pairings
