NNMT Enzyme Activity
Medicinal-chemistry studies evaluated 5-Amino-1MQ and related compounds for NNMT inhibition and enzyme-binding characteristics.
GLPZone / The research collection
Illustrative certificateNS-2026-06031Nordicstar Analytical Sciences
5-Amino-1MQ 5 MG
99.607%HPLC purity
- Lot
- GLZ-26-5AM1MQ-1030
- Measured content
- 5.03 mg
- Mass-spec identity
- Confirmed
- Endotoxin
- <1.0 EU/mg
- Tested
- 18 Sep 2026
Illustrative certificateNS-2026-06032Nordicstar Analytical Sciences
5-Amino-1MQ 50 MG
99.714%HPLC purity
- Lot
- GLZ-26-5AM1MQ-1031
- Measured content
- 50.2 mg
- Mass-spec identity
- Confirmed
- Endotoxin
- <1.0 EU/mg
- Tested
- 15 Sep 2026
Metabolic Research
5-Amino-1MQ
Small-molecule NNMT inhibition
A pair saves 10%. A set of three saves 15%.
For laboratory research use only.
Not for human consumption or clinical use.
Compound details
- Compound
- 5-Amino-1MQ
- CAS number
- 13496-08-9
- Molecular formula
- C10H10N2
- Molecular weight
- 158.20 g/mol
- Form
- Lyophilized
Quality & documentation
The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.
- Lot
- GLZ-26-5AM1MQ-1030
- HPLC purity
- 99.607%
- Measured content
- 5.03 mg
- Tested
- 18 Sep 2026
- Report
- NS-2026-06031
- Lot
- GLZ-26-5AM1MQ-1031
- HPLC purity
- 99.714%
- Measured content
- 50.2 mg
- Tested
- 15 Sep 2026
- Report
- NS-2026-06032
Shipping & handling
Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.
Shipping information01 / The compound
Understand
the starting point.
Small-molecule NNMT inhibition
5-Amino-1MQ, also known as 5-amino-1-methylquinolinium, is a synthetic small molecule studied as an inhibitor of nicotinamide N-methyltransferase (NNMT). Although it is frequently grouped with research peptides in product catalogs and search results, 5-Amino-1MQ is not a peptide.
Published research has investigated NNMT inhibition in biochemical assays, cultured cells and animal models related to cellular metabolism and skeletal-muscle biology. The evidence for 5-Amino-1MQ itself remains preclinical, so findings from these experimental models should not be interpreted as established human effects.
02 / Research profile
The pathways.
The possibilities.
NNMT is an enzyme that participates in nicotinamide metabolism. Early medicinal-chemistry research identified quinolinium compounds, including 5-Amino-1MQ, as small-molecule NNMT inhibitors and investigated how their structures interact with the enzyme's substrate-binding site.
Subsequent research evaluated 5-Amino-1MQ in cultured adipocytes and diet-induced-obesity mouse models, where NNMT inhibition was associated with changes in metabolic endpoints. Separate studies investigated NNMT inhibition in aged skeletal-muscle models, including muscle stem-cell activity, regeneration and muscle function.
These findings come from laboratory and animal models. They do not establish human efficacy, safety or an approved therapeutic use for 5-Amino-1MQ.
Metabolic Models
Cell and mouse research examined NNMT inhibition in adipocyte and diet-induced-obesity models.
Skeletal-Muscle Models
Mouse and cell studies investigated NNMT inhibition in muscle stem-cell, regeneration and age-related muscle-function models. Evidence level: biochemical, cellular and animal research. Human efficacy and safety have not been established.
Reading the evidence
The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.
03 / Reference data
The details,
in plain sight.
Reference specifications describe a compound. The final lot documentation identifies the material supplied.
| Compound | 5-Amino-1MQ |
|---|---|
| Research area | Metabolic Research |
| CAS number | 13496-08-9 |
| Molecular formula | C10H10N2 |
| Molecular weight | 158.20 g/mol |
| Physical form | Lyophilized |
| Vial options | 5 MG · 50 MG |
| Intended use | Laboratory research only |
Variant amounts are nominal catalog quantities. They are not instructions for use.
What is in the sample?
HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.
Is it the expected compound?
Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.
Does the report match the vial?
Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.
Independent analysis
Every 5-Amino-1MQ lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.
Read a COA with confidence| Presentation | Lot | HPLC purity | Tested | Certificate |
|---|---|---|---|---|
| 5 MG Current lot | GLZ-26-5AM1MQ-1030 | 99.607% | 18 Sep 2026 | NS-2026-06031 |
| 50 MG Current lot | GLZ-26-5AM1MQ-1031 | 99.714% | 15 Sep 2026 | NS-2026-06032 |
| 5 MG | GLZ-26-5AM1MQ-770 | 99.607% | 19 Aug 2026 | NS-2026-06133 |
| 50 MG | GLZ-26-5AM1MQ-769 | 99.614% | 13 Aug 2026 | NS-2026-06135 |
| 5 MG | GLZ-26-5AM1MQ-670 | 99.652% | 10 Jul 2026 | NS-2026-06134 |
| 50 MG | GLZ-26-5AM1MQ-669 | 99.576% | 08 Jul 2026 | NS-2026-06136 |
05 / Storage & handling
Care for
the material.
Avoid unnecessary temperature cycling and keep the vial tightly closed while in storage.
For prepared laboratory solutions, researchers should use a validated protocol appropriate to the solvent, concentration and experimental design.
Explore the handling guide06 / Common questions
A little more
understanding.
Is 5-Amino-1MQ a peptide?
No. 5-Amino-1MQ is a small-molecule quinolinium compound studied as an NNMT inhibitor. It is frequently grouped with research peptides commercially, but it is chemically distinct from a peptide and does not have an amino-acid sequence.
What is NNMT?
Nicotinamide N-methyltransferase, or NNMT, is an enzyme involved in nicotinamide metabolism. 5-Amino-1MQ has been investigated as a small-molecule inhibitor of NNMT in biochemical, cell and animal research.
07 / Further reading
Go to
the source.
Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.
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Curated pairings
