For laboratory research use only. Not for human consumption.

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Metabolic Research

GLP-3-RT

Retatrutide · GIPR, GLP-1R & glucagon receptor research

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Strength 10 MG
Vial quantity
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For laboratory research use only.
Not for human consumption or clinical use.

Compound details
Compound
GLP-3-RT
CAS number
2381089-83-2
Molecular formula
C221H343N53O68
Molecular weight
4731.4 g/mol
Form
Lyophilized
Quality & documentation

The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.

Lot
GLZ-26-GLP3RT-1000
HPLC purity
99.641%
Measured content
10.08 mg
Tested
25 Sep 2026
Report
NS-2026-06001
View the 10 MG certificate
Our quality approach
Shipping & handling

Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.

Shipping information
Explore the research profile
GLP-3-RT10 MG · Single
$79.00

01 / The compound

Understand
the starting point.

Retatrutide · GIPR, GLP-1R & glucagon receptor research

Retatrutide, also known by the development identifier LY3437943, is a synthetic peptide designed to interact with three receptor systems: the glucose-dependent insulinotropic polypeptide receptor, glucagon-like peptide-1 receptor and glucagon receptor.

Laboratory research has examined its multi-receptor pharmacology, receptor activation profile and signaling behavior. Its triple-agonist design makes it useful for studying how coordinated activity across GIPR, GLP-1R and GCGR differs from single- or dual-receptor agonism.

02 / Research profile

The pathways.
The possibilities.

Early Retatrutide research characterized the compound's molecular design and activity across GIP, GLP-1 and glucagon receptor systems.

The compound is particularly relevant to laboratory research examining multi-receptor agonism, receptor selectivity and the signaling consequences of combining three incretin- and glucagon-related pathways within a single peptide molecule.

Structural comparison across the three receptor complexes helps distinguish a shared agonist design from identical behavior at each target. Receptor selectivity and signaling remain separate experimental questions from a vial’s analytical purity.

01 / Research focus

GIPR

Retatrutide demonstrates agonist activity at the glucose-dependent insulinotropic polypeptide receptor. The original discovery research reported greater GIPR activity relative to its GCGR and GLP-1R activity.

02 / Research focus

GLP-1R

GLP-1 receptor agonism forms the second component of Retatrutide's multi-receptor research profile.

03 / Research focus

GCGR

Glucagon receptor agonism completes the compound's triple-receptor profile and distinguishes Retatrutide from peptides designed around only one or two of these receptor systems.

Reading the evidence

The selected literature concerns receptor structure, preclinical metabolic models and isolated tissue preparations. It establishes research context for the molecule, not purity, identity or performance of a GLPZone batch.

03 / Reference data

The details,
in plain sight.

Reference specifications describe a compound. The final lot documentation identifies the material supplied.

GLP-3-RT reference specifications
CompoundGLP-3-RT
Research areaMetabolic Research
CAS number2381089-83-2
Molecular formulaC221H343N53O68
Molecular weight4731.4 g/mol
Physical formLyophilized
Vial options10 MG · 15 MG · 20 MG · 30 MG · 40 MG · 50 MG · 60 MG
Intended useLaboratory research only

Variant amounts are nominal catalog quantities. They are not instructions for use.

04 / Quality & documentation

A number needs
its context.

How testing works
01 / Purity

What is in the sample?

HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.

02 / Identity

Is it the expected compound?

Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.

03 / Traceability

Does the report match the vial?

Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.

Independent analysis

Every GLP-3-RT lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.

Read a COA with confidence
GLP-3-RT lot certificates
PresentationLotHPLC purityTestedCertificate
10 MG Current lotGLZ-26-GLP3RT-100099.641%25 Sep 2026NS-2026-06001
15 MG Current lotGLZ-26-GLP3RT-100199.603%24 Sep 2026NS-2026-06002
20 MG Current lotGLZ-26-GLP3RT-100299.565%23 Sep 2026NS-2026-06003
30 MG Current lotGLZ-26-GLP3RT-100399.610%18 Sep 2026NS-2026-06004
40 MG Current lotGLZ-26-GLP3RT-100499.572%17 Sep 2026NS-2026-06005
50 MG Current lotGLZ-26-GLP3RT-100599.755%16 Sep 2026NS-2026-06006
60 MG Current lotGLZ-26-GLP3RT-100699.717%15 Sep 2026NS-2026-06007

05 / Storage & handling

Care for
the material.

Keep lyophilized Retatrutide protected from heat, light, and moisture.

For long-term storage of unopened research material, follow the handling information supplied with the product.

Explore the handling guide

06 / Common questions

A little more
understanding.

What is Retatrutide?

Retatrutide, also known as LY3437943, is a synthetic peptide studied for agonist activity at the GIP, GLP-1, and glucagon receptors.

How does a triple agonist differ from a dual agonist?

The retatrutide research profile includes GIPR, GLP-1R and GCGR. Tirzepatide is studied as a dual GIPR/GLP-1R agonist, while semaglutide is a selective GLP-1R agonist. These classifications describe receptor pharmacology rather than interchangeable material identities.

What kinds of retatrutide studies are cited?

The reference set includes receptor structural research, animal metabolic models and isolated mouse atrial preparations. Each addresses a different experimental question; findings from one model should not be generalized to the other.

07 / Further reading

Go to
the source.

Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.

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