For laboratory research use only. Not for human consumption.

Free U.S. shipping on $200+
GLPZonePeptides for laboratory research
0

GLPZone / The research collection

GLPZone GLP-1-SM, 10 MG vial
Illustrative certificateNS-2026-06008

Nordicstar Analytical Sciences

GLP-1-SM 10 MG

99.596%HPLC purity
Lot
GLZ-26-GLP1SM-1007
Measured content
10.07 mg
Mass-spec identity
Confirmed
Endotoxin
<1.0 EU/mg
Tested
18 Sep 2026
View Lab Report
Lyophilized

Metabolic Research

GLP-1-SM

Semaglutide · engineered GLP-1 receptor signaling

$44.00USD / vialView COA

A pair saves 10%. A set of three saves 15%.

Strength 10 MG
Vial quantity
  • Complimentary priority shipping from $200
  • Dispatched within 1–2 business days
  • Compare strengths and prices before ordering

For laboratory research use only.
Not for human consumption or clinical use.

Compound details
Compound
GLP-1-SM
CAS number
910463-68-2
Molecular formula
C187H291N45O59
Molecular weight
4113.6 g/mol
Form
Lyophilized
Quality & documentation

The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.

Lot
GLZ-26-GLP1SM-1007
HPLC purity
99.596%
Measured content
10.07 mg
Tested
18 Sep 2026
Report
NS-2026-06008
View the 10 MG certificate
Our quality approach
Shipping & handling

Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.

Shipping information
Explore the research profile
GLP-1-SM10 MG · Single
$44.00

01 / The compound

Understand
the starting point.

Semaglutide · engineered GLP-1 receptor signaling

Semaglutide is a synthetic 31-residue peptide analog of glucagon-like peptide-1 (GLP-1) and a selective GLP-1 receptor agonist. Its molecular design includes several modifications to native GLP-1 that increase resistance to enzymatic degradation and extend molecular exposure.

Key structural changes include an Aib substitution at position 8, an Arg substitution at position 34, and acylation at Lys26 with a linker and C18 fatty diacid. These modifications have made Semaglutide an extensively studied compound in GLP-1 receptor signaling, metabolic regulation and pharmacokinetic research.

02 / Research profile

The pathways.
The possibilities.

Semaglutide has been extensively investigated as a GLP-1 receptor agonist in molecular, biochemical, structural and preclinical research.

At the molecular level, Semaglutide differs from native GLP-1 through several engineered modifications, including an Aib substitution at position 8, an Arg substitution at position 34 and derivatization at Lys26 with a fatty-acid-containing side chain. These modifications influence enzymatic stability, albumin association and molecular exposure.

Structural research has also examined how Semaglutide engages the GLP-1 receptor. Cryo-electron microscopy studies of Semaglutide-bound GLP-1R–Gs complexes have characterized peptide-receptor interactions and receptor conformational dynamics associated with agonist binding.

Published findings should be interpreted within the specific experimental systems and conditions used in each study.

01 / Research focus

Aib8 — Enzymatic Stability

Alanine at GLP-1 position 8 is replaced with α-aminoisobutyric acid (Aib), increasing resistance to degradation by DPP-4.

02 / Research focus

Lys26 — Fatty-Acid Acylation

Lys26 carries a linker and C18 fatty diacid side chain that increases albumin binding and contributes to prolonged molecular exposure.

03 / Research focus

Arg34 — Sequence Modification

The Lys-to-Arg substitution at position 34 leaves Lys26 as the defined site used for side-chain attachment in Semaglutide's molecular design. Together, these modifications distinguish Semaglutide from native GLP-1 while preserving activity at the GLP-1 receptor.

Reading the evidence

The cited findings describe the compound in the experimental systems used. Cellular, biochemical and animal results should be interpreted according to their model, methods and endpoints; they do not establish the performance of a GLPZone lot.

03 / Reference data

The details,
in plain sight.

Reference specifications describe a compound. The final lot documentation identifies the material supplied.

GLP-1-SM reference specifications
CompoundGLP-1-SM
Research areaMetabolic Research
CAS number910463-68-2
Molecular formulaC187H291N45O59
Molecular weight4113.6 g/mol
Physical formLyophilized
Vial options10 MG · 15 MG · 20 MG · 30 MG
Intended useLaboratory research only

Variant amounts are nominal catalog quantities. They are not instructions for use.

04 / Quality & documentation

A number needs
its context.

How testing works
01 / Purity

What is in the sample?

HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.

02 / Identity

Is it the expected compound?

Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.

03 / Traceability

Does the report match the vial?

Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.

Independent analysis

Every GLP-1-SM lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.

Read a COA with confidence
GLP-1-SM lot certificates
PresentationLotHPLC purityTestedCertificate
30 MG Current lotGLZ-26-GLP1SM-101099.619%20 Sep 2026NS-2026-06011
20 MG Current lotGLZ-26-GLP1SM-100999.581%19 Sep 2026NS-2026-06010
10 MG Current lotGLZ-26-GLP1SM-100799.596%18 Sep 2026NS-2026-06008
15 MG Current lotGLZ-26-GLP1SM-100899.558%17 Sep 2026NS-2026-06009

05 / Storage & handling

Care for
the material.

Keep the vial sealed, dry and protected from unnecessary temperature fluctuations. Follow appropriate laboratory procedures when handling research material.

Explore the handling guide

06 / Common questions

A little more
understanding.

Is Semaglutide a peptide?

Yes. Semaglutide is a synthetic 31-residue peptide analog of GLP-1 that has been modified to increase stability and prolong molecular exposure.

Why distinguish peptide sequence positions from GLP-1 numbering?

Semaglutide is a 31-residue analogue, while labels such as Aib8, Lys26 and Arg34 use the native GLP-1 numbering convention. These modification positions describe the molecular design and are not a count of residues in the supplied peptide.

07 / Further reading

Go to
the source.

Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.

  1. 01
  2. 02
Our approach to research content

Curated pairings

Often studied together.

Explore the collection

Your research collection

Your bag 0

A new perspective awaits

Your bag is empty.

Explore the collection and find the compounds for your next research question.

Explore compounds

Find a research compound

Try GLP-3-RT, BPC-157, or NAD+.