For laboratory research use only. Not for human consumption.

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Metabolic Research

SS-31 (Elamipretide)

Cardiolipin, membrane biology & mitochondrial energetics

$88.00USD / vialView COA

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Strength 10 MG
Vial quantity
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For laboratory research use only.
Not for human consumption or clinical use.

Compound details
Compound
SS-31 (Elamipretide)
CAS number
736992-21-5
Molecular formula
C32H49N9O5
Molecular weight
639.79 g/mol
Form
Lyophilized
Quality & documentation

The records shown here are illustrative. Request laboratory-issued documentation for your lot before ordering.

Lot
GLZ-26-SS31-1032
HPLC purity
99.752%
Measured content
10.05 mg
Tested
16 Sep 2026
Report
NS-2026-06033
View the 10 MG certificate
Our quality approach
Shipping & handling

Priority, tracked shipping within the United States, free on orders of $200 or more after savings. Add Priority dispatch at checkout to have your order packed first; Private Clients receive it on every order. Follow the product documentation for laboratory handling requirements.

Shipping information
Explore the research profile
SS-31 (Elamipretide)10 MG · Single
$88.00

01 / The compound

Understand
the starting point.

Cardiolipin, membrane biology & mitochondrial energetics

SS-31, also known as elamipretide and historically as MTP-131, is a synthetic four-residue peptide developed for mitochondrial research. It belongs to the Szeto-Schiller class of aromatic-cationic peptides and has been investigated for its ability to associate with the inner mitochondrial membrane.

A major focus of SS-31 research is its interaction with cardiolipin, a phospholipid concentrated in the inner mitochondrial membrane and closely involved in membrane structure, respiratory-chain organization and mitochondrial bioenergetics. Modern research describes SS-31's activity more broadly than its earlier characterization as a simple mitochondrial antioxidant.

02 / Research profile

The pathways.
The possibilities.

Its aromatic-cationic structure has been studied in cardiolipin-containing membrane systems. The proposed mechanisms encompass lipid organization, membrane-surface electrostatics and mitochondrial bioenergetics, extending beyond an antioxidant-only description.

01 / Research focus

Cardiolipin & Mitochondrial Membranes

SS-31 has been investigated for its interaction with cardiolipin and cardiolipin-containing mitochondrial membrane systems. Experimental studies using membrane models and isolated mitochondria have examined how these interactions relate to mitochondrial membrane organization and bioenergetic processes.

02 / Research focus

Electron Transport & ATP Synthesis

Preclinical and biochemical research has examined SS-31 in relation to the cytochrome c/cardiolipin complex, mitochondrial electron transport and ATP synthesis. These studies provide mechanistic context for how SS-31 interacts with mitochondrial bioenergetic systems under controlled experimental conditions.

03 / Research focus

Membrane Electrostatics

Biophysical research has examined SS-31 binding to lipid bilayers and its effects on membrane-surface electrostatics. These findings have expanded the proposed mechanism beyond a simple antioxidant model and toward interactions involving membrane charge, lipid organization and cardiolipin-associated mitochondrial processes.

Reading the evidence

These findings come from biochemical, biophysical, cellular and animal experimental systems and should be interpreted within the specific models and conditions used in each study.

03 / Reference data

The details,
in plain sight.

Reference specifications describe a compound. The final lot documentation identifies the material supplied.

SS-31 (Elamipretide) reference specifications
CompoundSS-31 (Elamipretide)
Research areaMetabolic Research
CAS number736992-21-5
Molecular formulaC32H49N9O5
Molecular weight639.79 g/mol
Physical formLyophilized
Vial options10 MG · 50 MG
Intended useLaboratory research only

Variant amounts are nominal catalog quantities. They are not instructions for use.

04 / Quality & documentation

A number needs
its context.

How testing works
01 / Purity

What is in the sample?

HPLC separates components under a defined method. Read the reported percentage alongside the chromatogram, wavelength, integration method, and scope of the test.

02 / Identity

Is it the expected compound?

Mass spectrometry provides molecular-mass evidence. Identity and chromatographic purity answer different questions; one cannot stand in for the other.

03 / Traceability

Does the report match the vial?

Connect the product name, variant, lot identifier, report date, and issuing laboratory. A report is useful only when its sample can be linked to the material being reviewed.

Independent analysis

Every SS-31 (Elamipretide) lot is analyzed by Nordicstar Analytical Sciences for identity, content, and purity by HPLC with LC-MS confirmation. Each certificate carries a report number and verification key that can be checked at nordicstarlabs.com/verify. Research references below describe published science, not a certificate for a vial.

Read a COA with confidence
SS-31 (Elamipretide) lot certificates
PresentationLotHPLC purityTestedCertificate
50 MG Current lotGLZ-26-SS31-103399.721%21 Sep 2026NS-2026-06034
10 MG Current lotGLZ-26-SS31-103299.752%16 Sep 2026NS-2026-06033

05 / Storage & handling

Care for
the material.

Keep sealed research material protected from moisture, unnecessary light and temperature fluctuations. Use the storage conditions documented for the specific compound, formulation and lot.

Solution stability depends on solvent, concentration, container and experimental conditions. Use a validated laboratory protocol; a universal post-reconstitution shelf life is not established by the literature summaries.

Explore the handling guide

06 / Common questions

A little more
understanding.

What is SS-31?

SS-31, also known as elamipretide or MTP-131, is a synthetic tetrapeptide studied for its interaction with mitochondria and cardiolipin-rich inner mitochondrial membranes.

What is SS-31 studied for?

SS-31 is studied in mitochondrial research involving cardiolipin interactions, membrane electrostatics, electron transport, ATP synthesis and mitochondrial function across biochemical and preclinical models.

How is SS-31 related to cardiolipin?

Cardiolipin is a phospholipid concentrated in the inner mitochondrial membrane. Published studies have examined SS-31's interaction with cardiolipin-containing membranes and how those interactions may influence mitochondrial membrane organization and bioenergetic processes.

07 / Further reading

Go to
the source.

Selected literature for context. Read each study’s methods, experimental model, and limitations alongside its findings.

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